Advantages
Rich Experience
Fast Delivery
High Quality
One Stop Solution
Developed 3,000+
proteins and 20,000
antibodies
proteins and 20,000
antibodies
50 days for
polyclonal antibody
100 days for
monoclonal antibody
polyclonal antibody
100 days for
monoclonal antibody
ISO90012015,
AAALAC,
Lean-Sigma
AAALAC,
Lean-Sigma
Integrated with WuXi AppTec
platform
platform
Whole Process of antibody development
- Solubility, immunogenicity, epitope analysis
- peptide design
- Plasmid design
Peptide
- peptides synthesis
- from mg to gram,
- from crude to 99% purity
- Conjugation with carrier protein
Proteins
- 3000+ recombinant proteins
- E.coli, yeast, insect cell, mammalian cell certified
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- >30,000 m2
- hosts mouse, rabbit, rat, guinea pig, pig, goat, sheep, dog, monkey, etc.
- AAALAC, OECD, FDA and NMPA certified
- Conjugation with carrier protein
Polyclonal antibodies (PAb)
- >1,500 Pab yearly
- Custom PAb from gene ID to Ab in 3 months
- 20k+ catalog PAbs
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Monoclonal antibodies (MAb)
- Mouse or Rat Mab
- HTP Automatic screening Roller bottle and
- Wave bag culture
- >500 MAbs yearly certified
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Clinical Apps
- Antibody Hits
- Non-GLP production
- Diagnostic reagents and kits
Characterization
- IHC/ICC & kits
- ELISA & kits
- Western blotting
- Immunoprecipitation
- Confocal IF
- Flow cytometry
Reagents for large molecule bioanalysis
Recombinant proteins
Expression systems for recombinant protein include E.coli, yeast, insect and mammalian cells
Plasmid
Host cell
Culture
Purification
Vectors
- pET-21/22/28
- pPICK9K; pPICZa
- Bacmid; pFastBac
- pcNDA3.4; pcDNA4.0
- pOptiVec
- pFuse
- E.coli: BL21; Rosetta
- Yeast: Pichia pastoris
- Insect: Sf9; DH10Bac
-
Mammalian:
Expi CHO; Expi 293; G44
- Flask
- Wave bag
- From 50ml to 50 liters
- Ni2+Affinity
- GST
- Prote in A/G
- lon exchange
- Gel filtration
- Hydrophobic
Polyclonal antibody
Monoclonal antibody
Antibody pair against Exenatide
Monoclonal neutralizing anti-drug antibody
Anti-ID (idiotypic) Mab in house:
Humira, Avastin, Herceptin, Erbitux, Remicade, Rituxan, Perjeta, Actemra, Xgeva, Eylea
Humira, Avastin, Herceptin, Erbitux, Remicade, Rituxan, Perjeta, Actemra, Xgeva, Eylea
Antibody against small molecules
CDx, PD-L1 IHC Kit
QC of Procedure
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